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Avastin: Is It a Contender for Standard Therapy? PDF Print E-mail
Written by Dr Vasilev   
Saturday, 09 February 2008 18:00
Phase II data from the GOG (Gynecologic Oncology Group) for recurrent ovarian/primary peritoneal cancers, an ongoing similar confirmatory study, and an ongoing Phase III primary trial suggest that this is a true advance and may be part of future gold standard therapy.


Last Updated on Sunday, 10 February 2008 05:24
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OVArian TUmor REsponse (OVATURE) Study: A Promising New Strategy PDF Print E-mail
Written by Dr Vasilev   
Monday, 28 January 2008 13:17
Initially, ovarian cancer cells are usually very sensitive to chemotherapy. Unfortunately, at some point in time they lose sensitivity and develop "chemo-resistance", making successful treatment all but impossible.

Phenoxodiol, a synthetic variant of naturally occurring isoflavones found in multiple plants, has demonstrated an ability to kill cancer cells that are relatively resistant to standard chemotherapy drugs both in laboratory studies and in early phase clinical trials. 
Last Updated on Saturday, 16 February 2008 05:11
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New Therapies in Cancer Research PDF Print E-mail
Written by Dr Vasilev   
Sunday, 15 April 2007 05:51

Looking towards the future in cancer therapy, there are quite a few chemo drug and biological therapies in the pipeline being investigated.  For your review, this is a list of some of these compiled in early 2007.  As of early 2008, these are still in the running. Use the search engines on this site to look up more details.


 

Last Updated on Monday, 11 February 2008 11:36
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Surgeons and the President PDF Print E-mail
Written by Dr Vasilev   
Wednesday, 12 August 2009 16:27

I get political EXTREMELY rarely, but enough is enough.  I am getting more and more dismayed about leadership in this country and even more dismayed about misinformed and underpowered weakminded individuals thinking they are going to "reform" healthcare in the blink of an eye. 

Is there work to do to better the state of affairs?  Absolutely!  My experienced bias is that additional layers of bureaucracy is not the answer.  But more importantly the statements out there are getting moronic and counterproductive, and the President is apparently sounding like one of the morons. 

When one is charged with such a leadership role, there is no place for "oopsie" statements, particularly those that challenge the integrity of what is still one of the noblest professions around.  The rest is a quote from a statement which reflects the facts.

Statement from the American College of Surgeons Regarding Recent Comments from President Obama

CHICAGO--The American College of Surgeons is deeply disturbed over the uninformed public comments President Obama continues to make about the high-quality care provided by surgeons in the United States. When the President makes statements that are incorrect or not based in fact, we think he does a disservice to the American people at a time when they want clear, understandable facts about health care reform. We want to set the record straight.

Yesterday during a town hall meeting, President Obama got his facts completely wrong. He stated that a surgeon gets paid $50,000 for a leg amputation when, in fact, Medicare pays a surgeon between $740 and $1,140 for a leg amputation. This payment also includes the evaluation of the patient on the day of the operation plus patient follow-up care that is provided for 90 days after the operation. Private insurers pay some variation of the Medicare reimbursement for this service (Ed. almost always a lot LESS).


Three weeks ago, the President suggested that a surgeon's decision to remove a child's tonsils is based on the desire to make a lot of money. That remark was ill-informed and dangerous, and we were dismayed by this characterization of the work surgeons do. Surgeons make decisions about recommending operations based on what's right for the patient.


We agree with the President that the best thing for patients with diabetes is to manage the disease proactively to avoid the bad consequences that can occur, including blindness, stroke, and amputation. But as is the case for a person who has been treated for cancer and still needs to have a tumor removed, or a person who is in a terrible car crash and needs access to a trauma surgeon, there are times when even a perfectly managed diabetic patient needs a surgeon. The President's remarks are truly alarming and run the risk of damaging the all-important trust between surgeons and their patients.

We assume that the President made these mistakes unintentionally, but we would urge him to have his facts correct before making another inflammatory and incorrect statement about surgeons and surgical care.

American College of Surgeons
 

Last Updated on Wednesday, 12 August 2009 20:36
 
Avastin Plus Taxol for Breast Cancer: Is It Better? PDF Print E-mail
Written by Dr Vasilev   
Wednesday, 26 December 2007 12:07
The results of a clinical trial, published today in the New England Journal of Medicine, showed that the addition of  Avastin (Bevacizumab) to Taxol alone doubles progression free survival.  In other words, the amount of time that passes before there is evidence of recurrence is much longer.
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Cancer of the Ovary and HE4: A Promising Screening Test PDF Print E-mail
Written by Dr Vasilev   
Thursday, 20 December 2007 17:56
Four years ago, Seattle researchers identified a protein, known as Human Epididymis Protein 4 (HE4), as being highly effective in distinguishing cancer of the ovary from benign ovarian masses and cysts.   Since then additional studies have supported these initial findings, including one just published in the December 2007 edition of the journal Gynecologic Oncology. 
Last Updated on Saturday, 22 December 2007 09:09
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